- Chemical Name: 2,5-dibromobenzyl chloride
- CAS No.: 642091-49-4
Chemical plants supply high-quality 2,5-dibromobenzyl chloride 642091-49-4 in bulk
- Molecular Formula: C7H5Br2Cl
- Molecular Weight: 284.378
642091-49-4 Relevant articles
Synthetic method for 2,5-dibromophenylacetic acid
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Paragraph 0007; 0008; 0011; 0012; 0013; 0018, (2018/03/24)
The invention discloses a synthetic meth...
DIAMINE COMPOUND, POLYAMIC ACID, POLYIMIDE AND LIQUID CRYSTAL ALIGNING AGENT
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Paragraph 0345; 0349, (2016/12/01)
Disclosed is a novel diamine which has a...
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity
Szczepankiewicz, Bruce G.,Kosogof, Christi,Nelson, Lissa T. J.,Liu, Gang,Liu, Bo,Zhao, Hongyu,Serby, Michael D.,Xin, Zhili,Liu, Mei,Gum, Rebecca J.,Haasch, Deanna L.,Wang, Sanyi,Clampit, Jill E.,Johnson, Eric F.,Lubben, Thomas H.,Stashko, Michael A.,Olejniczak, Edward T.,Sun, Chaohong,Dorwin, Sarah A.,Haskins, Kristi,Abad-Zapatero, Cele,Fry, Elizabeth H.,Hutchins, Charles W.,Sham, Hing L.,Rondinone, Cristina M.,Trevillyan, James M.
, p. 3563 - 3580 (2007/10/03)
The c-Jun N-terminal kinases (JNK-1, -2,...
642091-49-4 Process route
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610-71-9
2,5-dibromobenzoic acid
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642091-49-4
2,5-dibromobenzyl chloride
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: 94 percent / BH3
*THF / tetrahydrofuran / 24 h / 20 °C
2: 91 percent / LiCl; SOCl2
/ dimethylformamide / 1.4 h / 20 °C
With
thionyl chloride; borane-THF; lithium chloride;
In
tetrahydrofuran; N,N-dimethyl-formamide;
|
|
|
With
methanesulfonyl chloride; triethylamine;
In
dichloromethane;
at 0 - 25 ℃;
for 26h;
Inert atmosphere;
Reflux;
|
8.19 g
|
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50-00-0,30525-89-4,61233-19-0
formaldehyd
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106-37-6
1.4-dibromobenzene
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642091-49-4
2,5-dibromobenzyl chloride
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; sodium chloride;
at 30 - 35 ℃;
for 40.5h;
Reagent/catalyst;
Temperature;
|
72%
|
642091-49-4 Upstream products
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147034-01-3
(2,5-dibromophenyl)methanol
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610-71-9
2,5-dibromobenzoic acid
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50-00-0
formaldehyd
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106-37-6
1.4-dibromobenzene
642091-49-4 Downstream products
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74553-29-0
2,5-dibromobenzaldehyde
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74533-21-4
2-(2,5-dibromophenyl)acetonitrile
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203314-28-7
2-(2,5-dibromophenyl)-acetic acid
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203314-51-6
(2,5-dibromo-phenyl)-acetyl chloride