- Chemical Name: 1-Phenylcyclopentylamine
- CAS No.: 17380-74-4
Quality products?make an important contribution to long-term revenue and profitability. Good factory exports good 1-Phenylcyclopentylamine 17380-74-4
1.What is the 1-Phenylcyclopentylamine ?
Used in Pharmaceutical Research:
1-Phenylcyclopentylamine is used as a research compound for the development of new psychoactive drugs with selective serotonin-releasing properties. Its unique structure and activity make it a valuable tool in understanding the mechanisms of serotonin release and the potential for treating mood disorders and depression.
Used in Mood Disorder Treatment:
1-Phenylcyclopentylamine is used as a potential treatment for mood disorders due to its potent and selective serotonin releasing action. Its ability to modulate serotonin levels in the brain may offer therapeutic benefits for individuals suffering from mood-related conditions.
Used in Antidepressant Development:
1-Phenylcyclopentylamine is used as a potential antidepressant, leveraging its SSRA properties to alleviate symptoms of depression. 1-Phenylcyclopentylamine's ability to release serotonin selectively may provide a more targeted approach to treating depressive disorders compared to traditional antidepressants.
Used in Recreational Drug Use:
Although not widely available for human consumption, 1-Phenylcyclopentylamine has been used recreationally due to its stimulant and euphoric effects. Its psychoactive properties have garnered interest among some individuals seeking altered states of consciousness or enhanced mood experiences. However, the recreational use of PCPA is not recommended due to potential health risks and legal implications.
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77-55-4
1-phenyl-1-cyclopentanecarboxylic acid
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17380-74-4
1-phenylcyclopentylamine
| Conditions | Yield |
|---|---|
|
1-phenyl-1-cyclopentanecarboxylic acid;
With
chloroformic acid ethyl ester; triethylamine;
In
water; acetone;
at 0 ℃;
for 0.5h;
With
sodium azide;
In
water; acetone;
at 0 ℃;
for 1h;
With
hydrogenchloride; tert-butyl alcohol;
more than 3 stages;
|
61%
|
|
Multi-step reaction
with
2
steps
1: SOCl2
/ dimethylformamide
2: (i) NaN3
, xylene, (ii) aq. HCl
With
thionyl chloride;
In
N,N-dimethyl-formamide;
|
-
-
66021-70-3
1-(1-azidocyclopentyl)benzene
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17380-74-4
1-phenylcyclopentylamine
| Conditions | Yield |
|---|---|
|
With
Raney nickel;
In
isopropyl alcohol;
at 60 - 70 ℃;
|
40%
|
|
With
lithium aluminium tetrahydride;
In
diethyl ether;
for 3h;
Yield given;
|
|
|
With
lithium aluminium tetrahydride;
In
diethyl ether;
at 20 ℃;
for 3h;
Inert atmosphere;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 3h;
Inert atmosphere;
|
291 mg
|
2.What is the CAS number for 1-Phenylcyclopentylamine ?
The CAS number of 1-Phenylcyclopentylamine is 17380-74-4.
More information of 1-Phenylcyclopentylamine 17380-74-4 are:
|
CAS?Number |
17380-74-4 |
|
Density |
1.014g/cm3 |
|
Boiling Point |
253.2 °C at 760 mmHg |
|
Flash Point |
110 °C |
|
Vapor Pressure |
0.0185mmHg at 25°C |
|
Refractive Index |
1.554 |
|
HS CODE |
2921499090 |
|
PSA |
26.02000 |
|
LogP |
3.11490 |
|
Pka |
9.63±0.20(Predicted) |
3.What are another words for 1-Phenylcyclopentylamine ?
Synonyms?for?1-Phenylcyclopentylamine 17380-74-4:Cyclopentylamine,1-phenyl- (7CI,8CI);1-Phenylcyclopentylamine;
4.What is the molecular formula of 1-Phenylcyclopentylamine?
The chemical formula of ?1-Phenylcyclopentylamine is?C11 H15 N which containing 11 Carbon atoms,15 Hydrogen atoms and 1 Nitrogen atoms,and the molecular weight of??1-Phenylcyclopentylamine?is 161.247.
5.What is 1-Phenylcyclopentylamine (17380-74-4) used for?
1-Phenylcyclopentylamine, also known as PCPA, is a chemical compound that belongs to the amphetamine class. It is a potent and selective serotonin releasing agent (SSRA) with potential therapeutic applications in mood disorders and as an antidepressant. PCPA is also a psychoactive drug with stimulant and euphoric effects, although it is not widely available for human consumption and is primarily used in research settings. Its structural similarity to other amphetamine derivatives makes it a valuable subject in medicinal chemistry for the development of new psychoactive drugs with selective serotonin-releasing properties.
InChI:InChI=1/C11H15N/c12-11(8-4-5-9-11)10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9,12H2
Relevant articles related to 1-Phenylcyclopentylamine:
|
Article |
Source |
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Synthesis and in Vitro Anticancer Activity of the First Class of Dual Inhibitors of REV-ERBβ and Autophagy |
Torrente, Esther,Parodi, Chiara,Ercolani, Luisa,De Mei, Claudia,Ferrari, Alessio,Scarpelli, Rita,Grimaldi, Benedetto supporting information, p. 5900 - 5915 (2015/08/24) |
|
Structure-guided design and synthesis of P1′ position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors |
Tagad, Harichandra D.,Hamada, Yoshio,Nguyen, Jeffrey-Tri,Hidaka, Koushi,Hamada, Takashi,Sohma, Youhei,Kimura, Tooru,Kiso, Yoshiaki experimental part, p. 5238 - 5246 (2011/10/08) |
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